![]() ![]() Differences in the specificity of reagent antibody clones and reagent formulations.Genetic variability in the strength of D antigen expression on some RBCs.Rh typing, on the other hand, can be equivocal due to four factors: Most discrepancies are typically attributed to sample or recording errors. What Causes Rh Blood Group Discrepancies?įor most blood group antigens, serologic testing reveals red blood cells (RBCs) to be either positive or negative for the antigen. ![]() This inconsistency then influences how OB-GYNs develop a treatment plan.īelow, we explore why Rh blood group discrepancies occur, what effect they have on obstetrics and how RHD genotyping may provide an effective solution. Anywhere from 2 to 4 percent of women can type as both Rh positive (D+) and Rh negative (D-). Sometimes, though, the results are anything but standard. My 1st baby was born at 41 weeks, had anti d at 28 and 33 weeks and following the birth, my 2nd baby was born at 40+16 very late baby huge too, anti d given also at 28 and 33 weeks, and not after delivery for some reason not sure of the reason why, and my 3rd baby born 7 weeks was born at 39 weeks via c-section due to the cord being wrapped around his neck, i had several anti d injections, one at 19 weeks due to a kid running into me, double dose at 25 weeks due to the dog jumping onto me, and a triple dose at 28 weeks which is normal as they don't do them at 33 weeks anymore, they are all just a precauction and nothing to be alarmed about.ĭon't worry about it all, i also read many horror stories on the net but sometimes i think you can worry yourself silly after reading things on here, but honestly all my babies were fine never had any problems at all and are all doing fine.Įnjoy your growing bump and before long you will have a little bundle in your arms xxxRh typing is a standard part of a woman’s first prenatal visit. I would like to point out that being Rh -, isn't such a bad thing, i too am Rh- and i've just had my 3rd baby, the first pregnancy is fine and the anti d injections is to prevent a blood crossing over and affecting future babies! Massive congtratulations on your pregnancy, what exciting times ahead for you. Thanks so much for reading this, any advice greatly appreciated I think I understand the basics of it all but I can't seem to grasp how serious/common this is from what I'm reading, some sites give really terrifying examples of babies needing blood transfusions after birth etc.Ī) once i have the anti D injections in the 3rd trimester, will this mean nothing can go wrong, or is there still a risk to my baby?ī) how common is in for the mothers blood and baby's blood to mix and is there anything I can do to prevent this?Ĭ) what are the odds that this won't affect my baby at all? My midwife, while lovely, does seem to rush through explaining things - I have since looked on the internet for a bit more info on all of this and really have got myself worked up about it. I had my 16 wk midwife check up on Friday, where I discovered from bloods taken at the first mw appointment that my blood type is O negative, and therefore there is a risk to me and my baby if our bloods mix and I need to have 'anti D injections'. I am 27 years old, 16 weeks pregnant with my first baby.
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